Troponin I

A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

Also Known As:

Troponin I1; Troponin I2; Troponin I3; Troponin-I

Macromolecular Substances: 97
- Polymers: 13529
  - Biopolymers: 836
    - Microfilament Proteins: 501
      - Troponin: 7017
        Troponin I: 4946
- Multiprotein Complexes: 128
  - Troponin: 7017
    - Troponin I: 4946
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Cytoskeletal Proteins: 743
    - Microfilament Proteins: 501
      - Troponin: 7017
        Troponin I: 4946
  - Contractile Proteins: 703
    - Muscle Proteins: 1603
      - Troponin: 7017
        Troponin I: 4946

Xifu Yan Selected Research

Xifu Yan Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure